The study investigated the influence of Teacher-parents relationships on academic performance of learners with hearing impairment in Akwa Ibom State. The Teacher-parents variables used in the study included Teacher-parents relationship, support and communication. Three research hypotheses were formulated to guide the study. The researcher made used of self-constructed instrument "questionnaire" (Teacher-parents Relationship Questionnaire (TPRQ)The descriptive survey research design was used for the study. The population of the study consists of forty-seven (47) senior secondary two (SS2) learners with hearing impairments of two (2) Special Schools (Ministry of Education Special centre, Mbiabong Etoi - (18 respondents and St. Louises Center for Inclusive Education, Ikot Ekpene - 29 respondents) respectively. The purposive sampling technique was used in selecting the samples that had the characteristics needed for the study. Data collected were analyzed using Z-test at 0.05 level of significance. Based on the findings, the researcher recommends that parents should consider the education of learners with hearing impairment as rewarding investment and make all necessary provisions to train them to become productive citizens to themselves and the society at large.