Our study aims to determine the observance and difficulties of application of the gluten-free diet among Moroccan celiac patients according to a sample of 60 patients facing the eating habits of the Moroccan population which is made up of a large part of the wheat. The response was defined by improvement in symptoms, 35% of patients were not observing all age groups combined especially in adolescents. The factors influencing compliance with the diet are: age at diagnosis, socio-economic level and level of education of the patient and small family. The main causes of non-compliance are the non-diversity and non-availability of gluten-free products as well as the high cost of these products. Adherence to the diet allows not only the improvement of symptoms but also the improvement of quality of life and the prevention of complications.