Cancer is the second-biggest cause of mortality globally. In 2018 alone, it was documented that nearly 9.6 million fatalities occurred because of cancer, in the ratio of one to six. The current study sought to establish whether oxidative stress occurs in breast and ovarian malignancies. The samples were collected from the tumor centers in Najaf from women who suffer from the required condition. The level of MDA in ovarian cancer patients was not significantly different from that of healthy women or ovarian vs. breast cancer patients. Patients with breast cancer had considerably greater amounts of lipid peroxidation products than healthy controls. Catalase activity in patients with ovary tumors was not different from that of the breast; however, there was a significant difference in catalase activity between patients with breast and ovarian cancers when compared to controls. In conclusion, the findings of present study indicate that oxidative stress is elevated in cancer patients, as seen by increased MDA and reduced catalase serum levels.