srjmsSRJMSSRJMS2788-9483https://doi.org/10.47310/srjms.2021.v01i01.009Estimating the Effect of 0.5% Levobupivacaine and its Adjuvant Dexamethasone on Sensory and Motor Functions: a Cross-Sectional Study in a Medical College of Rural IndiaVermaA.KGuptaRLevobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkyl substitute pipecoloxylidide. Specifically, the drug binds to the intracellular portion of sodium channels and blocks sodium influx into nerve cells, which prevents depolarization. It blocks nerve conduction in sensory and motor nerves mainly by interacting with voltage sensitive sodium channels on the cell membrane. It also interferes with impulse transmission and conduction in other tissues. Dexamethasone, a high-potency long-acting glucocorticoid has been shown to prolong peripheral nerve blockade and duration of analgesia as perineural adjuvant to bupivacaine. This study was aimed to assess the effect of 0.5% Levobupivacaine and its adjuvant 4 mg Dexamethasone on the sensory and motor functions of the nervous system through a USG guided supraclavicular plexus block. It was a cross sectional observational study that was conducted among the patients undergoing surgery at DRPGMC Kangra, Himachal Pradesh. The study was carried out over a period of 6 months. After excluding these patients, the total number of patients taken for the study were 30. Nearly 51 % participants were females.The majority of the study participants belonged to ASA grade one (80%) while the rest belonged to ASA grade two. the onset of sensory block was nearly 5 minutes. The duration for which the sensory block was maintained was 605 minutes. The time taken to attain the motor block using 0.5% levobupivacaine was around 10 minutes. The duration for which the motor block could be sustained was 570 minutes. The onset of sensory and motor blockade is quick in the patients being administered with 0.5% levobupivacaine mixed with the adjuvant dexamethasone 4 mg. The duration for which the motor and sensory block was attained was long. The patients enjoyed a painless interval between the onset through the offset of the anesthesia.