iarjimphIARJIMPHIARJIMPH2709-331Xhttps://doi.org/10.47310/iarjimph.2021.v02i02.013Failure to thrive and Congenital Heart Disease among Infants of Hilly RegionsBackground: Failure to thrive is slow physical development in a baby or child. It’s caused by a baby or child not having enough nutrition. The aim of the study is to find association between failure to thrive (FTT) and Congenital Heart Disease (CHD) in newborns/infants. Materials & Methods: This was a Cross-sectional observational study included children age between 0 to 1 year with suspected heart disease came to outdoor and indoor services of Department of Pediatrics IGMC, Shimla from July 2018 to June 2019. Results: In our study there were 102 participants in total. Out of them 57 participants were ≤1 month of age i.e. 57 (55.90 %) of total, 29 (28.4%) between 2-6 months, 16 (15.7%) between 7-12 months. There were 55 males and 47 females. In the present study, Failure to thrive was present in 17 (16.7%) out of 102 study participants. Failure to thrive was seen in 16 patients among all 79 diagnosed patients with CHD. Odd ratio was 0.22 with CI (0.03-1.57), with p-value of 0.14, which is not significant. The sensitivity, specificity, Positive Predictive Value (PPV) and Negative Predictive Value (NPV) of failure to thrive in diagnosing CHD is 20.2 %, 95.6%, 94.1 % and 25.88% respectively. Conclusion: It is important to determine whether failure to thrive results from congenital heart disease or factors in the environment, such as abuse or neglect.