iarjmsIARJMSIARJMS2708-3594https://doi.org/10.47310/iarjms.2023.v04i01.045Hypercortisolism an Omani Young Guy-A Case ReportJokhaSalim AlAbbadiaMohammedAlHarthyYahyaBin AbdullahAlrashdiCurrently, one of the big challenge to diagnostic the Cushing’s syndrome. Due to the disorders of hormones it will create major health problems such as hypertension, diabetics, rapid weight gain etc. It is a rare medical condition, usually caused by adrenal gland excessive cortisol secretion following a high adrenocorticotropic Hormone (ACTH) production from pituitary adenoma, excessive hypothalamic Corticotropin-Releasing Hormone (CRH) secretion, lung tumors, any other ectopic production, or exposure to glucocorticoids and chronic stress. In this present study is to describe a special case of Cushing’s syndrome and its diagnostic and symptoms. A 15-year-old Omani male patient diagnosed with ACTH dependent Cushing’s disease secondary to pituitary adenoma. Patient underwent two surgeries before disappearing his symptoms. He has also developed adrenal insufficiency due to hydrocortisone suspension. We highlight the importance of an accurate diagnosis and follow-up for successful management. In conclusion, Cushing’s syndrome is a rare medical problems and it diagnostic is complicated. When the patient diagnostic completed then it could be curable by surgical treatment.