iarjmsIARJMSIARJMS2708-3594https://doi.org/10.47310/iarjms.2021.v02i02.019Association of Recurrent chest infection and Congenital Heart Disease in Infants living at High AltitudeAbhinavGautamDeepakKumarSharmaBackground: There is a close relationship between Functions of the respiratory and cardiovascular systems. Congenital heart disease (CHD) affects the respiratory system and result in respiratory morbidities like recurrent chest infection. The aim of the study is to find association between Recurrent Chest Infection and Congenital Heart Disease (CHD) in newborns/infants living at High Altitude. Material and Methods: This was a Cross-sectional observational study included children age between 0 to 1 year with suspected heart disease came to outdoor and indoor services of Department of Pediatrics IGMC, Shimla from July 2018 to June 2019. Results: In our study there were 102 participants in total. Out of them 57 participants were ≤1 month of age i.e. 57(55.90 % of total, 29(28.4%) between 2-6 months,16(15.7%) between 7-12 months. There were 55 males and 47 females. In the present study, Recurrent chest infection was present in 18(17.6%) out of 102 study participants. In the present study, out of 79 study participants having underlying CHD, 18 (22.78%) had history of recurrent chest infections and all of them were diagnosed with underlying congenital heart disease with P value was 0.010 which was statistically significant. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of Recurrent chest infection in diagnosing CHD is 22.78 % ,100%, 100 % and 27.38% respectively. So, recurrent chest infection is a significant predictor of CHD as per our study. Conclusion: The study reveals that recurrent chest infections and CHD are closely associated. Recurrent chest infections can be considered as a significant parameter in diagnosis of CHD in children age less than one year living at high altitude.