iarjimphIARJIMPHIARJIMPH2709-331Xhttps://doi.org/10.47310/iarjimph.2021.v02i02.012Clinical Presentation of Congenital Heart Disease in Infants living at High AltitudeAmbikaSoodKatochRakeshSharmaDeepakSharmaBackground: Congenital heart diseases (CHDs) account for 6-10 % of all the infant deaths, and 20 - 40 % of all infant deaths from malformations. About 25% of CHDs are life threatening and manifest before the first routine clinical examination. The aim of the study is to identify clinical signs/symptoms that best predicts CHD in newborns/infants. Material and Methods: This was a Cross-sectional observational study included children age between 0 to 1 year with suspected heart disease came to outdoor and indoor services of Department of Pediatrics IGMC, Shimla from July 2018 to June 2019. The data was reported as frequency and percentages for categorical variables and mean ± sd for continuous variable Results: In our study there were 102 participants in total. Out of them 57 participants were ≤1 month of age i.e. 57(55.90 % of total, 29(28.4%) between 2-6 months,16 (15.7%) between 7-12 months. There were 55 males and 47 females. In the present study, tachycardia was present in 55(53.9%) out of 102 study participants, Failure to thrive in 17 (16.7%), Recurrent chest infection 18(17.6%), Suck rest suck cycle 32(31.4%), Forehead sweating 33(32.4%), Failure to maintain oxygen saturation84(82.4%) Increased precordial pulsations 26(25.5%) Murmur 76 (74.5%), Tachycardia 55(53.9%) and Cyanosis 28(27.5%). Conclusion: Forehead sweating, suck rest suck cycle, tachycardia, murmur, cyanosis, increased precordial pulsations, recurrent chest infections and spo2 can be considered as a significant parameter in screening of CHD in children age less than one year living at high altitude.