iarjmcrIARJMCRIARJMCR2709-3220https://doi.org/10.47310/iarjmcr.2022.v03i01.013Acute Megakaryoblastic Leukemia (LAM 7): About A CaseSalmaRouhiSalouaAbbassiWafaaQuiddiSanaeSayaghLaboratory of Hematology Laboratory, Mohammed VI University Hospital Marrakech, Morocco and Faculty of Medicine and Pharmacy, Cadi Ayyad University, Marrakech, MoroccoAcute megakaryoblastic leukemia is a very rare entity of Acute Myeloid Leukemia (AML), usually with a severe prognosis. It is extremely rare in adults, occurring in only 1% of AML patients. This is in contrast to children, where it included between 4 and 15% of AML patients. Its diagnosis calls for a multidisciplinary approach. Based primarily on the presence in the blood or in the bone marrow of blasts with a typical morphology of the megakaryocytic line. This is superseded by immunophenotyping for blasts expressing specific platelet antigens. The epidemiological, clinical, cytological and immunophenotypic aspects of acute megakaryoblastic leukemia (AMegL) are described through this observation of a 2-year-old kid who presented with bone marrow failure syndrome and bi-cytopenia.