Contents
Download PDF
pdf Download XML
1072 Views
266 Downloads
Share this article
Research Article | Volume 4 Issue 3 (May, 2023)
A Comparative Study of the Nalbuphine with Fentanyl with Fentanyl as An Adjuvant to Hyperbaric 0.5% Bupivacaine in Spinal Anaesthesia
Under a Creative Commons license
Open Access
Published
June 19, 2023
Abstract
Introduction This study aims to evaluatethe safety and the efficacy of Nalbuphine with fentanyl as an intrathecal adjuvant to hyperbaric bupivacaine. The objective to study the onset and duration of sensory blockage; time to two segment regression; hemodynamic changes. Material and Methods Two groups of thirty ASA Gr I and II patients of either gender were randomly assigned. Group I patients will get 0.8 mg (1 ml) of nalbuphine and 12.5 mg (2.5 ml) of 0.5 percent hyperbaric bupivacaine. Group II patients will receive 12.5 mg and 25 μg of Fentanyl (1 ml). Hemodynamics, sensory and motor block, early postoperative analgesia, and side effects were examined. The study included 18–55-year-old male and female patients. The study excluded patients with cardiac arrhythmias, heart blocks, or bradycardia; a known allergy to the test drug; a gross spinal abnormality, localised skin sepsis, haemorrhagic diathesis, neurological involvement/diseases; head injuries or raised intracranial pressure; and hemodynamic instability. Results Number of rescue analgesia in 24 hrs was significantly less needed among Hyperbaric bupivacaine with nalbuphine group. Systolic blood pressure fluctuation was high among hyperbaric bupivacaine with fentanyl than Hyperbaric bupivacaine with nalbuphine group. Diastolic blood pressure fluctuation was relatively greater among hyperbaric bupivacaine with fentanyl than nalbuphine group. SPO2 saturation fluctuation was almost similar in both the groups. The fluctuation between the groups was not statistically significant. Among hyperbaric bupivacaine with nalbuphine group 4 reported sedation and two reported nausea. Among hyperbaric bupivacaine with fentanyl group two had chest pain. Conclusion In this clinical study, nalbuphine added to hyperbaric bupivacaine at 0.5 percent was more efficient than fentanyl at enhancing postoperative analgesia and extending sensory motor blockade without increasing unpleasant effects.
Keywords
Recommended Articles
Research Article
A Comparative Study of the Nalbuphine with Fentanyl with Fentanyl as an Adjuvant to Hyperbaric 0.5% Bupivacaine in Spinal Anaesthesia
Published: 17/05/2023
Download PDF
Chat on WhatsApp
Flowbite Logo
PO Box 101, Nakuru
Kenya.
Email: office@iarconsortium.org

Editorial Office:
J.L Bhavan, Near Radison Blu Hotel,
Jalukbari, Guwahati-India
Useful Links
Order Hard Copy
Privacy policy
Terms and Conditions
Refund Policy
Shipping Policy
Others
About Us
Contact Us
Online Payments
Join as Editor
Join as Reviewer
Subscribe to our Newsletter
+91 60029-93949
Follow us
MOST SEARCHED KEYWORDS
Copyright © iARCON International LLP . All Rights Reserved.